【病毒外文文獻】2014 766Clinical Features and Outcome of Patients with Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) Infection

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766 Clinical Features and Outcome of Patients with Middle East Respiratory Syndrome Coronavirus MERS CoV Infection Basem Alraddadi MD MS Noha Bawareth MD Haneen Omar Hanadi Alsalmi MS Maun Feteih MD Ghassan Wali MD King Faisal Specialist Hospital and Research Centre Jeddah Saudi Arabia Session 106 Clinical Respiratory Infections Friday October 10 2014 12 30 PM Background The number of laboratory con rmed cases of Middle East Respira tory Syndrome Corona Virus is increasing and has been associated with high mortality rate Our aim is to describe clinical features and outcome of patients infected with MERS CoV in a tertiary hospital outbreak in Jeddah Saudi Arabia Methods We reviewed the medical records of 30 patients with con rmed MERS CoV infections during hospital outbreak between April 7 until April 30 2014 We fol lowed WHO de nitions for con rmed MERS CoV infection Results A total of 30 patients were diagnosed with con rmed MERS CoV infec tion 16 patients were health care workers The mean age was 43 years SD 16 5 Sev enteen patients were male 54 8 Majority of patients N 20 66 7 were symptomatic on presentation Fever was the most presenting symptoms N 20 66 7 followed by cough N 18 60 Although only 10 patients 35 7 reported shortness of breath on presentation 27 patients 93 1 had abnormal chest xary In terms of laboratory ndings 13 patients 54 2 had lymphopenia on presentation Signi cant number of patients developed progressive respiratory disease 9 patients 30 required mechanical ventilation and 12 patients 38 7 required ICU admission Conclusion Fever and abnormal chest x ray were the most common clinical fea tures in patients with MERS CoV infection Signi cant numberof MERS CoV patient s required mechanical ventilation and ICU admission Disclosures All authors No reported disclosures S208 OFID 2014 1 Suppl 1 Poster Abstracts Downloaded from by guest on 26 October 2019